Image-based analysis of lipid nanoparticle-mediated siRNA delivery, intracellular trafficking and endosomal escape : Nature Biotechnology : Nature Publishing Group

Reference genomes are required to understand the diverse roles of microorganisms in ecology, evolution, human and animal health, but most species remai

A low-error 16S ribosomal RNA amplicon sequencing method, in combination with whole-genome sequencing of >500 cultured isolates, was used to characteri

Delivery of short interfering RNAs (siRNAs) remains a key challenge in the development of RNA interference (RNAi) therapeutics. A better understanding

New high-dimensional, single-cell technologies offer unprecedented resolution in the analysis of heterogeneous tissues. However, because these technolo

In the version of this article initially published, there were two errors in the discussion of epigenetic marks on page 854. In sentence 4, paragraph 2

Genetic mutations causing human disease are conventionally thought to be inherited through the germ line from one’s parents and present in all somatic

Cell-based therapies for myelin disorders, such as multiple sclerosis and leukodystrophies, require technologies to generate functional oligodendrocyte

Transplantation of oligodendrocyte precursor cells (OPCs) is a promising potential therapeutic strategy for diseases affecting myelin. However, the der

It is currently not possible to predict which epitopes will be recognized by T cells in different individuals. This is a barrier to the thorough analys

Dysfunction of basal forebrain cholinergic neurons (BFCNs) and γ-aminobutyric acid (GABA) interneurons, derived from medial ganglionic eminence (MGE),