Short sleep and weight gain are inversely related. Sleep deprivation acutely increases food intake but little is known about eating behavior in chronically sleep-deprived, obese individuals.
To characterize the relationship between sleep, food intake and alcohol consumption under free-living conditions in obese, chronically sleep-deprived individuals.
Cross-sectional study of a cohort of obese men and premenopausal women.
A total of 118 obese subjects (age: 40.3±6.7 years; 91 females/27 males; body mass index 38.7±6.4 kg m−2).
Energy, macronutrient, alcohol and caffeine intake assessed by 3-day food records. Sleep duration estimated by actigraphy. Respiratory disturbance index assessed by a portable device.
Subjects slept 360.7±50.2 min per night and had a total energy intake of 2279.1±689 kcal per day. Sleep duration and energy intake were inversely related (r=−0.230, P=0.015). By extrapolation, each 30-min deficit per day in sleep duration would translate to an ~83 kcal per day increase in energy intake. In addition, sleep apnea was associated with a shift from carbohydrate to fat intake. Alcohol intake in subjects consuming >3.5 g of alcohol per day (N=41) was inversely related to sleep duration (r=−0.472, P=0.002).
受试者每晚睡眠长度约为360.7 ± 50.2分钟并且每天摄入总能量约为2279.1 ± 689千卡。睡眠长度和能量摄入呈负相关性（r = -0.230，P = 0.015）。通过外推法得知，每天每减少30分钟睡眠长度则将约增加83千卡能量的摄入。此外，睡眠呼吸暂停与碳水化合物转变为脂肪摄入量的转换有关。当每个受测者每天摄入超过3.5克酒精时，酒精摄入量（N = 41）与睡眠长度呈负相关（r = -0.472 ， P = 0.002）。
Shorter sleep duration and obstructive sleep apnea are associated with higher energy, fat and alcohol intakes in obese individuals. The importance of this study relies on the population studied, obese subjects with chronic sleep deprivation. These novel findings apply to the large segment of the US population who are obese and sleep-deprived.
Keywords: sleep apnea, public health, CPAP, epidemic