唧唧堂编辑二朵2014-01-01 1:51 AM

Inverse relationship of food and alcohol intake to sleep measures in obesity 肥胖症中食物和酒精摄入与睡眠方法成反比

Abstract 摘要 Background: Short sleep and weight gain are inversely related. Sleep deprivation acutely increases food intake but little is known about eating behavior in chronically sleep-deprived, obese individuals. 背景: 短暂睡眠和体重增加成反比。睡眠不足能敏锐地增加食物摄入量,但对慢性失眠肥胖者的饮食行为仍所知甚少。 Objective: To characterize the relationship between sleep, food intake and alcohol consumption under free-living conditions in obese, chronically sleep-deprived individuals. 目的: 确认长期失眠的肥胖者在自由生活条件下睡眠,食物摄入和饮酒间的联系。 Design: Cross-sectional study of a cohort of obese men and premenopausal women. 设计: 对肥胖男性和绝经前妇女组群的横断面研究。 Subjects: A total of 118 obese subjects (age: 40.3±6.7 years; 91 females/27 males; body mass index 38.7±6.4 kg m−2). 主题: 共有118名肥胖受测者 (年龄:40.3±6.7岁;91 名女性/27名男性,身体质量指数38.7±6.4千克M^−2)。 Measurements: Energy, macronutrient, alcohol and caffeine intake assessed by 3-day food records. Sleep duration estimated by actigraphy. Respiratory disturbance index assessed by a portable device. 方法: 能量,营养素,酒精和咖啡因摄入量通过3天的饮食记录进行评估。睡眠长度由活动记录检查仪进行估计。呼吸紊乱指数由便携式设备进行测评。 Results: Subjects slept 360.7±50.2 min per night and had a total energy intake of 2279.1±689 kcal per day. Sleep duration and energy intake were inversely related (r=−0.230, P=0.015). By extrapolation, each 30-min deficit per day in sleep duration would translate to an ~83 kcal per day increase in energy intake. In addition, sleep apnea was associated with a shift from carbohydrate to fat intake. Alcohol intake in subjects consuming >3.5 g of alcohol per day (N=41) was inversely related to sleep duration (r=−0.472, P=0.002). 结果: 受试者每晚睡眠长度约为360.7 ± 50.2分钟并且每天摄入总能量约为2279.1 ± 689千卡。睡眠长度和能量摄入呈负相关性(r = -0.230,P = 0.015)。通过外推法得知,每天每减少30分钟睡眠长度则将约增加83千卡能量的摄入。此外,睡眠呼吸暂停与碳水化合物转变为脂肪摄入量的转换有关。当每个受测者每天摄入超过3.5克酒精时,酒精摄入量(N = 41)与睡眠长度呈负相关(r = -0.472 , P = 0.002)。 Conclusions: Shorter sleep duration and obstructive sleep apnea are associated with higher energy, fat and alcohol intakes in obese individuals. The importance of this study relies on the population studied, obese subjects with chronic sleep deprivation. These novel findings apply to the large segment of the US population who are obese and sleep-deprived. 结论: 较短的睡眠长度和睡眠呼吸暂停与肥胖者更高的能量,脂肪以及酒精摄入量有关。本研究重点在于所选取的慢性失眠肥胖者研究样本群体。这些新发现适用于大部分美国失眠肥胖群体。 Keywords: sleep apnea, public health, CPAP, epidemic 关键词:睡眠呼吸暂停,公共卫生, CPAP治疗,疫情

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