唧唧堂编辑二朵2014-03-21 3:22 PM

[MDPI][营养学]蒙莫朗西樱桃能缓解多日高强度随机骑行的氧化应激和炎症反应 Montmorency Cherries Reduce the Oxidative Stress and Inflammatory Responses to Repeated Days High-Intensity Stochastic Cycling 

论文摘要
本次调查研究了蒙莫朗西酸樱桃浓缩物(MC)对3日模拟道路自行车赛的氧化应激,炎症和肌肉损伤的生理指标产生的影响。职业骑行赛手(N = 16 )被平均分组并要求连续七天按每天两次的剂量服用30毫升MC或安慰剂(PLA)。然后让他们在第5,6,7天参加了时长109分钟的高强度随机骑行模拟赛。我们在赛前和赛后分别立即测量了所采集的基线量血液样品的氧化应激和炎症,且对脂质过氧化物(LOOH),白细胞介素-6(IL-6),肿瘤坏死因子-α(TNF-α),白细胞介素-8(IL-8),白细胞介素1 -β(IL-1-β),高敏C-反应蛋白(hsCRP)和肌酸激酶(CK)进行了分析。相较于安慰剂对照组,服用樱桃浓缩物组对模拟赛的LOOH(P <0.01),IL- 6(P <0.05)和C反应蛋白(P<0.05)反应表现较低。我们未发现任何团体或交互效应对另一标记有反应。减毒氧化和炎症反应表明樱桃浓缩物可能对对抗运动后氧化和炎症级联反应有效,这会导致细胞破裂。此外,我们证实了在多日骑行和假象的其他必有背对背对抗行为的竞赛情况中樱桃浓缩物的直接临床应用。

Abstract 
This investigation examined the impact of Montmorency tart cherry concentrate (MC) on physiological indices of oxidative stress, inflammation and muscle damage across 3 days simulated road cycle racing. Trained cyclists (n = 16) were divided into equal groups and consumed 30 mL of MC or placebo (PLA), twice per day for seven consecutive days. A simulated, high-intensity, stochastic road cycling trial, lasting 109 min, was completed on days 5, 6 and 7. Oxidative stress and inflammation were measured from blood samples collected at baseline and immediately pre- and post-trial on days 5, 6 and 7. Analyses for lipid hydroperoxides (LOOH), interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-α), interleukin-8 (IL-8), interleukin-1-beta (IL-1-β), high-sensitivity C-reactive protein (hsCRP) and creatine kinase (CK) were conducted. LOOH (p < 0.01), IL-6 (p < 0.05) and hsCRP (p < 0.05) responses to trials were lower in the MC group versus PLA. No group or interaction effects were found for the other markers. The attenuated oxidative and inflammatory responses suggest MC may be efficacious in combating post-exercise oxidative and inflammatory cascades that can contribute to cellular disruption. Additionally, we demonstrate direct application for MC in repeated days cycling and conceivably other sporting scenario’s where back-to-back performances are required. 

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