Science2014-06-11 12:33 PM

微型移动性健康监测 Soft Microfluidic Assemblies of Sensors, Circuits, and Radios for the Skin

论文摘要  

如果一位孕妇或一名罹患慢性疾病的患者能够将某种用于监测其健康的昂贵医院设备—如心电图(ECG)机—带回家中,那会是怎样的一副情景呢?由Sheng Xu及其同事所采用的一种非常接近这种构想的新的方法,这种方法通过可舒适地附着于一个人皮肤上的薄的、具有弹性的装置并以无线方式进行电生理数据监测;他们所用的新的方法包括了悬浮于液体中的传感器、电路及无线电微型组建。他们说,这种技术具有在诊所范围之外提供持续的、具有医院品质的医疗监测的潜力。通过软性微流控与结构性粘性表面的结合及受到控制的机械屈曲,Xu及其他的研究人员能够设计出可拉伸的电路板——它具有微型的电子元件,这些元件通过弯曲形的相互联系网络而连接在一起;该电路板悬浮在多聚物溶液中并受到硅酮橡胶膜的牵制。他们的新的策略将这类医疗检测装置的延展性及机械顺应性同时改善了几个数量级,且研究人员提出,这些软性、柔韧性的装置有一天将可从患者自己舒适的家中提供有关他们的准确、实时的健康信息。

Abstract 

When mounted on the skin, modern sensors, circuits, radios, and power supply systems have the potential to provide clinical-quality health monitoring capabilities for continuous use, beyond the confines of traditional hospital or laboratory facilities. The most well-developed component technologies are, however, broadly available only in hard, planar formats. As a result, existing options in system design are unable to effectively accommodate integration with the soft, textured, curvilinear, and time-dynamic surfaces of the skin. Here, we describe experimental and theoretical approaches for using ideas in soft microfluidics, structured adhesive surfaces, and controlled mechanical buckling to achieve ultralow modulus, highly stretchable systems that incorporate assemblies of high-modulus, rigid, state-of-the-art functional elements. The outcome is a thin, conformable device technology that can softly laminate onto the surface of the skin to enable advanced, multifunctional operation for physiological monitoring in a wireless mode.

KEYWORDS

SHARE & LIKE

COMMENTS

ABOUT THE AUTHOR

Science

Science Magazine

0 Following 18 Fans 0 Projects 236 Articles

SIMILAR ARTICLES

AbstractThe conservation of sleep across all animal species suggests that sleep serves a vital function. We here report that sleep has a critical funct

Read More

Introduction Recent decades have seen a major international effort to inventory tree communities in the Amazon Basin and Guiana Shield (Amazonia), but

Read More

IntroductionInitiation of protein synthesis is a key step in the control of gene expression. In eukaryotes, initiation is a highly complex process that

Read More

Abstract For decades, social psychological theories have posited that the automatic processes captured by implicit measures have implications for soci

Read More

论文摘要动物界最复杂的眼睛可以在物种口足类甲壳动物(濑尿虾)中找到,其中一些有12种不同类型的光感受器,每种各取样较窄的一组波长,范围包含了深紫外光到远红光(300到720纳米)。在功能上,这种彩色复杂性被视作是谜。当3种或4种色彩通道对色彩辨认来说已经足够时,为何要使用12种色彩通道?对口足类动物行

Read More

论文摘要 首先,在一篇“评论”文章中,Thomas Piketty 和 Emmanuel Saez用“世界顶级收入数据库(WTID)”来比较这两个数值多年来是如何在欧洲和美国演变的;WTID包括了一个世纪之久的有关全球收入的数据以及2个世纪之久的有关个人财富的数据。据研究人员披露,在20世纪之交的时候

Read More

IntroductionCensorship has a long history in China, extending from the efforts of Emperor Qin to burn Confucian texts in the third century BCE to the c

Read More

Many animals, on air, water, or land, navigate in three-dimensional (3D) environments, yet it remains unclear how brain circuits encode the animal's 3D

Read More

Many animals, on air, water, or land, navigate in three-dimensional (3D) environments, yet it remains unclear how brain circuits encode the animal's 3D

Read More

Like mammalian neurons, Caenorhabditis elegans neurons lose axon regeneration ability as they age, but it is not known why. Here, we report that let-7

Read More