JIJITANG2014-11-24 6:03 PM

ARSENIC ON TAP MAY CUT BREAST CANCER DEATHS




We tend to think of arsenic as a poison , but new research links high levels of the element in drinking water to a 50 percent drop in breast cancer deaths .


The study , published in the journal EBioMedicine , presents results of breast cancer mortality data from a region in Chile where residents were inadvertently exposed to high levels of arsenic , which occurs naturally in many minerals .


Instead of an increase in mortality , as with many other cancer sites, the study found that breast cancer deaths were cut in half during the period that coincided with high arsenic exposure . The effect was more pronounced among women under age 60, with mortality in these women reduced by 70 percent .


“What we found was astonishing , ” says study lead author Allan Smith , professor of epidemiology at University of California , Berkeley , and director of the Arsenic Health Effects Research Program . 


“We’ve been studying the long-term effects of arsenic in this population for many years , focusing on increased disease and mortality attributed to the historical exposure to arsenic in this population .”


In 1958 , the northern Chilean city of Antofagasta switched to a geothermal water source originating in the Andes Mountains. Years later , it was discovered that the water sources contained more than 800 micrograms per liter of arsenic—80 times higher than the levels recommended by the World Health Organization .


An arsenic removal plant was installed in 1970 after toxic effects from arsenic exposure became apparent in some residents .


CLINICAL TRIALS


As part of the study , researchers at the Stanford Cancer Institute found that human breast cancer cells grown in lab cultures are killed by arsenic , and normal breast cells are more resistant to arsenic .


The medicinal use of arsenic is not entirely new . Arsenic trioxide was approved in 2000 by the Food and Drug Administration as an effective treatment for a rare type of leukemia .


So should arsenic now be used to treat breast cancer ?


“Not yet ,” says Smith .“ We do not know if the treatment will work , but carefully designed clinical trials should take place as soon as possible based on this new evidence .”


Smith and collaborators in Chile are proceeding to design clinical trials in which some advanced breast cancer patients would be given arsenic treatment .


Additional coauthors contributed from Pontifical Catholic University of Chile , UC Berkeley , and Stanford University .



Original Article :

《Rapid Reduction in Breast Cancer Mortality With Inorganic Arsenic in Drinking Water》, Published on Journal《EBioMedicine》on 13th  October , 2014 .


http://www.jijitang.com/article/5472c3d163c5da8d682ebe97

KEYWORDS

SHARE & LIKE

COMMENTS

ABOUT THE AUTHOR

JIJITANG

0 Following 3 Fans 0 Projects 310 Articles

SIMILAR ARTICLES

Changes to the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) have resulted in families eating more fruits and vegetable

Read More

In contests drawn from game theory, chimpanzee pairs consistently outperform humans in games that test memory and strategic thinking.A new study, condu

Read More

Publishing is one of the most ballyhooed metrics of scientific careers, and every researcher hates to have a gap in that part of his or her CV. Here’s

Read More

Pornography triggers brain activity in people with compulsive sexual behaviour -- known commonly as sex addiction -- similar to that triggered by drugs

Read More

In a recent survey, academic staff at the University identified the interrelated skills of writing and reasoning as the two most important skills for s

Read More

In a recent survey, academic staff at the University identified the interrelated skills of writing and reasoning as the two most important skills for s

Read More

Reading cautionary tales like The Boy Who Cried Wolf and Pinocchio to little kids might not be the best way to teach them to tell the truth.New researc

Read More

Those flat, glassy solar panels on your neighbor’s roof may be getting a more efficient makeover, thanks to a new class of solar-sensitive nanoparticle

Read More

Physicists have overcome a major challenge in the science of measurement using quantum mechanics. They’ve used multiple detectors to measure photons in

Read More

If you want to slow down long enough to smell the proverbial roses, you might want to move to a neighborhood with fewer drive-thru restaurants, researc

Read More