Journal of Abnormal Psychology2015-03-31 9:09 PM

Kindling of Life Stress in Bipolar Disorder: Comparison of Sensitization and Autonomy Models

Abstract:

Research on life stress in bipolar disorder largely fails to account for the possibility of a dynamic relationship between psychosocial stress and episode initiation. The kindling hypothesis (Post, 1992) states that over the course of recurrent affective disorders, there is a weakening temporal relationship between major life stress and episode initiation that could reflect either a progressive sensitization or progressive autonomy to life stress. The present study involved a comprehensive and precise examination of the kindling hypothesis in 102 participants with bipolar II disorder that allowed for a direct comparison of sensitization and autonomy models. Polarity-specific tests were conducted across the continuum of event severity with respect to impact and frequency of life events. Hypotheses were polarity- and event-valence specific and were based on the stress sensitization model. Results were only partially consistent with the sensitization model: Individuals with more prior mood episodes had an increased frequency of minor negative events before depression and of minor positive events before hypomania. However, the number of past episodes did not moderate relationships between life events and time until prospective onset of mood episodes. These results are more consistent with a sensitization than an autonomy model, but several predictions of the sensitization model were not supported. Methodological strengths, limitations, and implications are discussed regarding putative changes in stress reactivity that may occur with repeated exposure to mood episodes in bipolar II disorder.

Full Text

KEYWORDS

SHARE & LIKE

COMMENTS

ABOUT THE AUTHOR

Journal of Abnormal Psychology

The Journal of Abnormal Psychology publishes articles on basic research and theory in the broad field of abnormal behavior, its determinants, and its correlates.

0 Following 2 Fans 0 Projects 15 Articles

SIMILAR ARTICLES

Abstract:Research on life stress in bipolar disorder largely fails to account for the possibility of a dynamic relationship between psychosocial stress

Read More

AbstractSocial anxiety disorder is known to be associated with self-report of global friendship quality. However, information about specific friendship

Read More

A growing body of longitudinal studies suggests that low self-esteem is a risk factor for depression. However, it is unclear whether other characterist

Read More

Pervasive doubts are a central feature of obsessive–compulsive disorder (OCD). We have theorized that obsessive doubts can arise in relation to any int

Read More

Chronic alcohol abuse is a major public health concern following trauma exposure; however, little is known about the temporal association between postt

Read More

Lee, Jooa Julia; Gino, Francesca; Staats, Bradley R.Journal of Applied Psychology, Vol 99(3), May 2014, 504-513.AbstractPeople believe that weather con

Read More

Yam, Kai Chi; Fehr, Ryan; Barnes, Christopher M.Journal of Applied Psychology, Vol 99(6), Nov 2014, 1288-1299.In this research, we draw from the stereo

Read More

Judge, Timothy A.; Cable, Daniel M.Journal of Applied Psychology, Vol 96(1), Jan 2011, 95-112. AbstractCultivation theory suggests that society holds v

Read More

Shoss, Mindy K.; Eisenberger, Robert; Restubog, Simon Lloyd D.; Zagenczyk, Thomas J.Journal of Applied Psychology, Vol 98(1), Jan 2013, 158-168. Abstra

Read More

Long-Zeng Wu1, Ho Kwong Kwan1,*, Li-Qun Wei2 andJun Liu3AbstractOver two decades, social influence researchers have called for a study that would exami

Read More